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Evaluation of lipid-bound sialic acid tumor marker in sera of acute lymphocytic (ALL) patients

Journal of Baghdad College of Dentistry

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Title Evaluation of lipid-bound sialic acid tumor marker in sera of acute lymphocytic (ALL) patients
 
Creator Hamad, Abdul Wahab R.
Talabani, Nazar G.A.
Al-Swad, Fawaz
 
Description Background: Lipid-bound sialic acid (LSA) concentration was determined in the sera of 90 patients with acute
lymphocytic leukemia (ALL) and 50 controls (30 normal subjects and 20 chronic non-malignant diseases). The aim of
this work is to determine the reference values for serum sialic acid in healthy subjects and in patients with acute
lymphocytic leukemia.
Materials and Method: All of serum sample were collected by venepuncture and kept frozen (-20 C°) until analyzed,
then a spectrophotometric technique is used for the estimation of the concentration of sialic acid marker in sera.
Results: The mean sialic concentration in healthy individuals was 132 mg/ml and that in chronic non-malignant
disease was 171.1 mg/ml, where as, the concentration of (LSA) in 90 cancer patients with (ALL) was 270.3 mg/ml.
Conclusion: Both cancer patients with (ALL) and patients with chronic non-tumor disease can cause an elevation in
the concentration of sialic acid values in serum as compared to healthy individuals.
 
Publisher College of dentistry/ University of baghdad
 
Date 2017-01-31
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Identifier http://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/1688
 
Source Journal of Baghdad College of Dentistry; Vol 20 No 1 (2008); 28-30
2311-5270
1680-0087
 
Language en
 
Rights Copyright (c) 2017 Journal of Baghdad College of Dentistry