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Role of Diffusion-Weighted MR Imaging in Characterization of Posterior Fossa Tumors

AL-Kindy College Medical Journal

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Title Role of Diffusion-Weighted MR Imaging in Characterization of Posterior Fossa Tumors
 
Creator Hussain, Lubna Ali
 
Description Background: Conventional  MR imaging is essential for diagnosis and evaluation of the posterior fossa tumors  Objectives: To assess the value of diffusion weighted imaging and apparent diffusion coefficient in making distinction between different histological types of posterior fossa tumors.
Type of the study: Cross-sectional study.
Methods: Brain MRI and DWI assessed 19 patients (12 female and 7 male) with MRI diagnosis of posterior fossa tumors. absolute ADC values of contrast -enhancing solid tumor region and ADC ratio of solid tumor to ADC of normal -appearing deep White matter were compared with histological diagnosis postoperatively .The mean ADC value and ratio were determined by using a 2-tailed T test. Results: In eight of  medulloblastoma ,The mean  ADC value was 0.67±0.14x 10-3 mm 2/s  and  ratio 0.86±0.19  ,   ependymoma (n=3), ADC value 1.09 ±0.14 x10 -3 mm 2 /s and ratio 1,43±0.13   ,  pilocytic astrocytoma (n=4) ADC value 1,72 ±0.27x10 -3 mm2/s and ratio 2.19±0.4, brainstem glioma (n=2) with ADC value1.18±0.06 x10-3mm2/s and ratio 1.64±0.08 , haemangioblastoma  (n=1) with ADC value1.46x10-1mm2/s and ratio 1.87 , and meningioma with ADC value 0.72x10-3mm2/s and ratio 0.85. ADC values were higher in JPA than in ependymomas and medulloblastoma (P value <o,o5).ADC ratio were also  statistically significant difference among these three tumors type .
Conclusion: calculation of apparent diffusion coefficient value in the solid enhancing portion of tumor   seems to be reliable for  differentiate between  medulloblastoma at one end and , juvenile pilocytic astrocytoma (JPA) and ependymoma at other end as the former has ADC of < 1 while other tumors have ADC value of >1.
 
Publisher AL-Kindy College Medical Journal
 
Date 2018-10-10
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier http://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/journal%40kmc.uobaghdad.edu.iq
 
Source مجلة كلية طب الكندي; مجلد 14 عدد 1 (2018): AL-KINDY COLLEGE MEDICAL JOURNAL; 8-12
AL-Kindy College Medical Journal; Vol 14 No 1 (2018): AL-KINDY COLLEGE MEDICAL JOURNAL; 8-12
2521-4365
1810-9543
 
Language eng
 
Relation http://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/journal%40kmc.uobaghdad.edu.iq/10
 
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