Determination Of Micro Amount Of Spironolactone In Some Of Pharmaceutical Preparate By Using a Molecular Luminescence Technique.
Baghdad Science Journal
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| Title |
Determination Of Micro Amount Of Spironolactone In Some Of Pharmaceutical Preparate By Using a Molecular Luminescence Technique.
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| Creator |
Journal, Baghdad Science
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| Description |
The present study include a new developed method of analysis for determination of drug Spironolaction (SP) in some Pharmaceuticals by Spectrofluorometric method. Spironolaction was determined under optimal experimental condition that follows :- The excitation spectrum was (l=351 nm), the emmetion spectrum was (l=518 nm), pH=1, the suitable temperature for reaction 60oC and the optimal time less than (3) minute. The analysis and rang statistical data was:-Linear dynamic rang (1-10) ?g.ml-1, the detection limit (D.L = 0.023 ?g.ml-1), Molar absorptivity (? = 29875 liter mole-1 cm-1), Relative standard deviation (%RSD = 0.78), (%Erel = 3.3) and recovery (Rec = 96.6) percentage. Determination of Spironolactone was accomplished by two methods (A) Using direct calibration curve method, Corr. Coef. (R = 0.988 and %Rec = 97.4). (B) Using standard additional methods Corr. Coef (R =0.988 and %Rec= 96.6). |
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| Publisher |
College of Science for Women - University of Baghdad
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| Date |
2008-03-02
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| Type |
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion Peer-reviewed Article |
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| Format |
application/pdf
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| Identifier |
http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/862
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| Source |
مجلة بغداد للعلوم; مجلد 5 عدد 1 (2008): issue 1; 55-62
Baghdad Science Journal; Vol 5 No 1 (2008): issue 1; 55-62 2411-7986 2078-8665 |
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| Language |
eng
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| Relation |
http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/862/793
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| Rights |
Copyright (c) 2008 Baghdad Science Journal
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