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Estimation of cellular immune response by evaluation of some cytokines in immunopathogenesis of chronic hepatitis B and C pre- and post- treated Iraqi patients (in vivo and in vitro)

Baghdad Science Journal

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Title Estimation of cellular immune response by evaluation of some cytokines in immunopathogenesis of chronic hepatitis B and C pre- and post- treated Iraqi patients (in vivo and in vitro)
 
Creator Journal, Baghdad Science
 
Description Two groups of chronic hepatitis B and C virus patients were divided into Pre-treated patients (25 CHB patients with positive HBs Ag for more than 6 months and 40 CHC patients), and post-treated patients [12 CHB patients (4, 6, and 2 were treated with lamivudine, IFN-? and combination of LMV + IFN-? respectively), and 27 patients for CHC (3, 13 and 11 patients were treated with Ribavirin, IFN-? and combination therapy (RBV+ IFN-?) respectively].These patients were followed up for 6 months.
By using ELISA technique, levels of IL-6, IL-10, IFN-? and TNF-? were measured in vivo and in vitro (supernatant of PBMCs stimulated with PHA) and compared with healthy control. The mean level of IL-6, IL-10 and TNF-? in CHB patients showed significant differences (P
 
Publisher College of Science for Women - University of Baghdad
 
Date 2009-09-06
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1013
 
Source مجلة بغداد للعلوم; مجلد 6 عدد 3 (2009): issue 3; 533-541
Baghdad Science Journal; Vol 6 No 3 (2009): issue 3; 533-541
2411-7986
2078-8665
 
Language eng
 
Relation http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1013/944
 
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