Record Details

The Effect of Aqueous Extract of Citrullius colocynthis Seeds on Cellular Immunity

Baghdad Science Journal


Field	Value

Title	The Effect of Aqueous Extract of Citrullius colocynthis Seeds on Cellular Immunity

Creator	Journal, Baghdad Science

Description	The aqueous extract of Citrullius colocynthis dried seeds (160 ?g/ml) was in vitro evaluated for its effect on phagocytic index (PI) and lymphocyte transformation index (LTI) of blood cells obtained from 30 apparently healthy blood donors (15 males and 15 females). The PI was further in vivo evaluated in cells of peritone, spleen and liver of mice treated with the extract at a dose of 0.64 mg/kg. The results revealed that in in vitro study, phagocytic cells treated with the extract showed a significant increased percentage as compared with untreated cells (60.0 vs. 44.1%). Phagocytes obtained from peritone (44.1 vs. 30.0%) and spleen (45.6 vs. 39.6 %) of treated and untreated mice behaved in a similar manner, while liver phagocytes showed no significant difference between PI of immunological function of the investigated cells, and may use as therapeutic agent. treated and untreated mice. For LTI, cultures I and II shared an approximated mean (70.0 and 68.0%, respectively), but both indices were significantly higher than the recorded LTI in culture III (54.0%). These findings suggest that the plant extract is effective in enhancing the

Publisher	College of Science for Women - University of Baghdad

Date	2012-12-02

Type	info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article

Format	application/pdf

Identifier	http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1409

Source	مجلة بغداد للعلوم; مجلد 9 عدد 4 (2012): issue 4; 651-655 Baghdad Science Journal; Vol 9 No 4 (2012): issue 4; 651-655 2411-7986 2078-8665

Language	eng

Relation	http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1409/1340

Rights	Copyright (c) 2012 Baghdad Science Journal