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Serum and salivary levels of proinflammatory cytokines as potential biomarkers in the diagnosis of oral squamous cell carcinoma

Journal of Baghdad College of Dentistry

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Title Serum and salivary levels of proinflammatory cytokines as potential biomarkers in the diagnosis of oral squamous cell carcinoma
 
Creator Al Talabani , Nazar G
Gaphor , Shanaz M
Hamad , Abdul-Wahab R
 
Description Background: Oral squamous cell carcinoma is one of the prevalent cancers of the body . If not treated at its early stages, the prognosis will be poor. Early diagnosis of oral cancer may not be easy clinically because of itsresemblance to a number of benign lesions in the mouth. The aim of the study was to evaluate the validity of measurement of some proinflammatory cytokines levels in serum and saliva asbiomarkers for early detection of oral cancer.
Materials and methods: The levels of Interleukins IL-1?, IIL-6, IL-8 and Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) in the serum and saliva of (30) patients with OSCC and (20) healthy (control) individuals weremeasured by enzyme linked immunosorbent assay (ELISA).
Results: Higher concentrations of serum IL-6 and IL-8 levels were observed in patients with OSCC than the control group (P
 
Publisher College of dentistry/ University of baghdad
 
Date 2013-12-29
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier http://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/115
 
Source Journal of Baghdad College of Dentistry; Vol 21 No 1 (2009); 60-65
2311-5270
1680-0087
 
Language eng
 
Relation http://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/115/pdf_9
 
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